Open Syndrome Syphilis congenital and neonatal

{
   "category": "suspected",
   "definition_type": "case_definition",
   "description": "",
   "human_readable_definition": "Any infant aged 0–\u003c 2 years with at least one of the following ten:\n– Hepatosplenomegaly\n– Mucocutaneous lesions\n– Flat warts\n– Persistent rhinitis\n– Jaundice\n– Pseudoparalysis (due to periostitis and osteochondritis)\n– Signs from the central nervous system\n– Anemia\n– Nephrotic syndrome\n– Reduced food intake",
   "inclusion_criteria": [
     {
       "logical_operator": "AND",
       "name": "Age \u003c 2 years and at least 1 symptom",
       "type": "criterion",
       "values": [
         {
           "attribute": "age",
           "description": "\u003c 2 years",
           "name": "age",
           "operator": "\u003c=",
           "type": "demographic_criteria",
           "unit": "years",
           "value": 2
         },
         {
           "logical_operator": "AT_LEAST",
           "logical_operator_arguments": [
             1
           ],
           "name": "With at least one of the following ten symptoms",
           "type": "criterion",
           "values": [
             {
               "name": "hepatosplenomegaly",
               "type": "symptom"
             },
             {
               "name": "mucocutaneous lesions",
               "type": "symptom"
             },
             {
               "name": "flat warts",
               "type": "symptom"
             },
             {
               "name": "persistent rhinitis",
               "type": "symptom"
             },
             {
               "name": "jaundice",
               "type": "symptom"
             },
             {
               "name": "Pseudoparalysis (due to periostitis and osteochondritis)",
               "type": "symptom"
             },
             {
               "name": "Signs from the central nervous system",
               "type": "symptom"
             },
             {
               "name": "anemia",
               "type": "symptom"
             },
             {
               "name": "nephrotic syndrome",
               "type": "symptom"
             },
             {
               "name": "reduced food intake",
               "type": "symptom"
             }
           ]
         }
       ]
     }
   ],
   "keywords": [
     "Syphilis",
     "Europe"
   ],
   "language": "English",
   "location": "Greece",
   "open_syndrome_version": "1.0.0",
   "organization": "National Public Health Organization",
   "published_at": "2025-02-08T11:15:13Z",
   "published_by": [
     "Open Syndrome Initiative"
   ],
   "published_in": "https://opensyndrome.org",
   "references": [
     {
       "url": "https://eody.gov.gr/wp-content/uploads/2022/04/orismoi-loimodon-nosimaton-20220413.pdf"
     }
   ],
   "scope": "broad",
   "status": "draft",
   "target_public_health_threats": [
     "Syphilis"
   ],
   "title": "Open Syndrome Syphilis congenital and neonatal",
   "version": "1.0.0"
 }