Open Syndrome Respiratory syncitial virus (RSV)
Table of Contents
Authors: Omer, Saad B. PhD, Bednarczyk, Robert PhD, Kazi, Momin MBBS, Guterman, L. Beryl MSPH, Aziz, Fatima MBBS, Allen, Kristen E. MPH, Yildirim, Inci PhD, Ali, S. Asad MBBS, Hubert Department of Global Health
Location: Pakistan
Purpose #
Wheeze or apnea or cyanosis
The definition #
severe chest indrawing with either cough or tachypnea
Machine-readable definition #
The definition is available in JSON format following the Open Syndrome v1.0 specification:
{
"authors": [
"Omer, Saad B. PhD",
"Bednarczyk, Robert PhD",
"Kazi, Momin MBBS",
"Guterman, L. Beryl MSPH",
"Aziz, Fatima MBBS",
"Allen, Kristen E. MPH",
"Yildirim, Inci PhD",
"Ali, S. Asad MBBS"
],
"category": "suspected",
"definition_type": "case_definition",
"description": "Wheeze or apnea or cyanosis",
"human_readable_definition": "severe chest indrawing with either cough or tachypnea",
"inclusion_criteria": [
{
"logical_operator": "AND",
"name": "Severe chest indrawing",
"type": "criterion",
"values": [
{
"name": "Severe chest indrawing",
"type": "symptom"
},
{
"logical_operator": "OR",
"name": "Either cough or tachypnea",
"type": "criterion",
"values": [
{
"name": "Cough",
"type": "symptom"
},
{
"name": "Tachypnea",
"type": "symptom"
}
]
}
]
}
],
"keywords": [
"Respiratory syncytial virus",
"Asia"
],
"language": "English",
"location": "Pakistan",
"notes": [
"The syndromic screening definitions included:\n“wheeze or apnea or cyanosis” (the classic manifestation of RSV) (section Screening and Sample Selection, second paragraph)"
],
"open_syndrome_version": "1.0.0",
"organization": "Hubert Department of Global Health",
"published_at": "2025-01-29T12:00:00Z",
"published_by": [
"Open Syndrome Initiative"
],
"published_in": "https://opensyndrome.org",
"references": [
{
"citation": "Omer, Saad B. PhD*,†,‡,§; Bednarczyk, Robert PhD*,†,§; Kazi, Momin MBBS; Guterman, L. Beryl MSPH*; Aziz, Fatima MBBS; Allen, Kristen E. MPH*; Yildirim, Inci PhD†,‡; Ali, S. Asad MBBS. Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population. The Pediatric Infectious Disease Journal 38(3):p e57-e59, March 2019. | DOI: 10.1097/INF.0000000000002159",
"url": "https://journals.lww.com/pidj/Fulltext/2019/03000/Assessment_and_Validation_of_Syndromic_Case.29.aspx"
}
],
"scope": "specific",
"status": "draft",
"target_public_health_threats": [
"Respiratory syncytial virus"
],
"title": "Open Syndrome Respiratory syncitial virus (RSV)",
"version": "1.0.0"
}
Using the Definition #
Healthcare organizations can implement this definition through:
- Direct integration with surveillance systems
- API endpoints for real-time validation
- Manual case verification processes
Next Steps #
We encourage:
- Clinical feedback on the definition criteria
- Technical feedback on the implementation format
- Suggestions for additional symptoms or signs
- Reports of implementation experiences
Get Involved #
We welcome contributions and feedback from the community.