Open Syndrome Nipah Like Illness
Table of Contents
Authors:
Location: Bangladesh
Purpose #
The definition #
Fever (axillary temperature > 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of brain pathology OR Fever (axillary temperature > 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of lung pathology
Machine-readable definition #
The definition is available in JSON format following the Open Syndrome v1.0 specification:
{
"category": "suspected",
"definition_type": "case_definition",
"description": "",
"human_readable_definition": "Fever (axillary temperature \u003e 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of brain pathology\nOR\nFever (axillary temperature \u003e 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of lung pathology",
"inclusion_criteria": [
{
"logical_operator": "AND",
"type": "criterion",
"values": [
{
"logical_operator": "OR",
"type": "criterion",
"values": [
{
"name": "Fever (axillary temperature \u003e38.5°C)",
"type": "symptom"
},
{
"name": "history of raised temperature prior to hospitalization",
"type": "professional_judgment"
}
]
},
{
"logical_operator": "AND",
"type": "criterion",
"values": [
{
"name": "any sign/symptom of lung pathology",
"type": "symptom"
},
{
"name": "any sign/symptom of brain pathology",
"type": "symptom"
}
]
}
]
}
],
"keywords": [
"Nipah virus",
"Asia"
],
"language": "English",
"location": "Bangladesh",
"open_syndrome_version": "1.0.0",
"organization": "",
"published_at": "2025-01-29T12:00:00Z",
"published_by": [
"Open Syndrome Initiative"
],
"published_in": "https://opensyndrome.org",
"references": [
{
"citation": "Satter SM, Aquib WR, Sultana S, Sharif AR, Nazneen A, et al. (2023) Tackling a global epidemic threat: Nipah surveillance in Bangladesh, 2006–2021. PLOS Neglected Tropical Diseases 17(9): e0011617.",
"url": "https://doi.org/10.1371/journal.pntd.0011617"
}
],
"scope": "broad",
"status": "draft",
"target_public_health_threats": [
"Nipah virus"
],
"title": "Open Syndrome Nipah Like Illness",
"version": "1.0.0"
}
Using the Definition #
Healthcare organizations can implement this definition through:
- Direct integration with surveillance systems
- API endpoints for real-time validation
- Manual case verification processes
Next Steps #
We encourage:
- Clinical feedback on the definition criteria
- Technical feedback on the implementation format
- Suggestions for additional symptoms or signs
- Reports of implementation experiences
Get Involved #
We welcome contributions and feedback from the community.