Open Syndrome Influenza-like Illness (ILI)
Table of Contents
Authors: Ministry of Health
Location: Brazil
Purpose #
Standardized case definition of suspected influenza-like illness for adults
The definition #
Indivíduo que apresente febre de início súbito, mesmo que referida, acompanhada de tosse ou dor de garganta e pelo menos um dos seguin- tes sintomas: cefaleia, mialgia ou artralgia, na ausência de outro diagnós- tico específico.
Machine-readable definition #
The definition is available in JSON format following the Open Syndrome v1.0 specification:
{
"category": "suspected",
"definition_type": "case_definition",
"description": "Standardized case definition of suspected influenza-like illness for adults",
"exclusion_criteria": [
{
"description": "Presence of any other specific diagnosis that explains the symptoms",
"name": "Other specific diagnosis",
"type": "diagnosis"
}
],
"human_readable_definition": "Indivíduo que apresente febre de início súbito, mesmo que referida,\nacompanhada de tosse ou dor de garganta e pelo menos um dos seguin-\ntes sintomas: cefaleia, mialgia ou artralgia, na ausência de outro diagnós-\ntico específico.",
"inclusion_criteria": [
{
"logical_operator": "AND",
"type": "criterion",
"values": [
{
"description": "Sudden onset fever, even if self-reported",
"name": "Fever",
"type": "symptom"
},
{
"logical_operator": "OR",
"type": "criterion",
"values": [
{
"name": "Cough",
"type": "symptom"
},
{
"name": "Sore throat",
"type": "symptom"
}
]
},
{
"logical_operator": "AT_LEAST",
"logical_operator_arguments": [
1
],
"type": "criterion",
"values": [
{
"name": "Headache",
"type": "symptom"
},
{
"name": "Myalgia",
"type": "symptom"
},
{
"name": "Arthralgia",
"type": "symptom"
}
]
}
]
}
],
"keywords": [
"Influenza-like Illness (ILI)",
"South America"
],
"language": "English",
"location": "Brazil",
"open_syndrome_version": "1.0.0",
"organization": "Ministry of Health",
"published_at": "2025-01-29T12:00:00Z",
"published_by": [
"Open Syndrome Initiative"
],
"published_in": "https://opensyndrome.org/case-definitions",
"references": [
{
"url": "https://www.gov.br/ebserh/pt-br/hospitais-universitarios/regiao-sudeste/hc-ufu/saude/epidemiologia/protocolos/protocolo/protocolo-de-sindrome-gripal-e-sindrome-respiratoria-aguda-grave-com-enfase-em-influenza"
}
],
"scope": "specific",
"status": "draft",
"target_public_health_threats": [
"Influenza-like Illness (ILI)"
],
"title": "Open Syndrome Influenza-like Illness (ILI)",
"version": "1.0.0"
}
Using the Definition #
Healthcare organizations can implement this definition through:
- Direct integration with surveillance systems
- API endpoints for real-time validation
- Manual case verification processes
Next Steps #
We encourage:
- Clinical feedback on the definition criteria
- Technical feedback on the implementation format
- Suggestions for additional symptoms or signs
- Reports of implementation experiences
Get Involved #
We welcome contributions and feedback from the community.