Open Syndrome Dengue Fever
Table of Contents
Authors: Vector Borne Disease Sector - Disease Control Division, Ministry of Health
Location: Malaysia
Purpose #
The definition #
Acute onset of high grade fever of usually 2-5 days or more associated with two or more of the following: headache, retro-orbital pain, myalgia, arthralgia, rash and mild haemorrhagic manifestation (epistaxis, gums bleeding and petechiae).
Machine-readable definition #
The definition is available in JSON format following the Open Syndrome v1.0 specification:
{
"authors": [
"Vector Borne Disease Sector - Disease Control Division"
],
"category": "suspected",
"definition_type": "case_definition",
"description": "",
"human_readable_definition": "Acute onset of high grade fever of usually 2-5 days or more associated with two or more\nof the following: headache, retro-orbital pain, myalgia, arthralgia, rash and mild\nhaemorrhagic manifestation (epistaxis, gums bleeding and petechiae).",
"inclusion_criteria": [
{
"logical_operator": "AND",
"type": "criterion",
"values": [
{
"name": "Acute onset of high grade fever of usually 2-5 days or more",
"type": "symptom"
},
{
"logical_operator": "AT_LEAST",
"logical_operator_arguments": [
2
],
"name": "Other symptoms",
"type": "criterion",
"values": [
{
"name": "headache",
"type": "symptom"
},
{
"name": "retro-orbital pain",
"type": "symptom"
},
{
"name": "myalgia",
"type": "symptom"
},
{
"name": "arthralgia",
"type": "symptom"
},
{
"name": "rash",
"type": "symptom"
},
{
"description": "e.g. epistaxis, gums bleeding and petechiae",
"name": "mild haemorrhagic manifestation",
"type": "symptom"
}
]
}
]
}
],
"keywords": [
"Dengue",
"Arbovirosis",
"Asia"
],
"language": "English",
"location": "Malaysia",
"open_syndrome_version": "1.0.0",
"organization": "Ministry of Health",
"published_at": "2025-01-29T12:00:00Z",
"published_by": [
"Open Syndrome Initiative"
],
"published_in": "https://opensyndrome.org",
"references": [
{
"citation": "Case Definition of Infectious Disease 3rd Edition 2017",
"url": "https://www2.moh.gov.my/moh/resources/Penerbitan/Garis%20Panduan/Pengurusan%20KEsihatan%20\u0026%20kawalan%20pykit/Case_Definition_Of_Infectious_Disease_3rd_Edition_2017.pdf"
}
],
"scope": "broad",
"status": "draft",
"target_public_health_threats": [
"Dengue fever"
],
"title": "Open Syndrome Dengue Fever",
"version": "1.0.0"
}
Using the Definition #
Healthcare organizations can implement this definition through:
- Direct integration with surveillance systems
- API endpoints for real-time validation
- Manual case verification processes
Next Steps #
We encourage:
- Clinical feedback on the definition criteria
- Technical feedback on the implementation format
- Suggestions for additional symptoms or signs
- Reports of implementation experiences
Get Involved #
We welcome contributions and feedback from the community.