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  1. Case Definitions/

Open Syndrome Cold Exposure

Authors: Ministerio de Salud

Location: Argentina

Purpose #

Case definition for suspected cold exposure in individuals with history of extreme cold exposure during Early Temperature Extreme Alert by National Meteorological Service, and clinical symptoms attributable to low body temperature (36°C or lower) and 2 or more of the following: shivering, altered consciousness, weak pulse, slow breathing, local tissue damage due to freezing.

The definition #

Toda persona con antecedentes de exposición a frío extremo en circunstancia de Alerta Temprana por Temperatura Extrema (frío) del Servicio Meteorológico Nacional, y sintomatología clínica atribuible. Temperatura corporal igual o menor a 36 ºC y 2 o más de los siguientes síntomas, a saber: Signos y síntomas atribuibles: escalofríos, alteración del estado de conciencia, pulso débil, bradipnea, daño tisular local causado por el enfriamiento. Piel fría y roja en bebés.

Machine-readable definition #

The definition is available in JSON format following the Open Syndrome v1.0 specification:

{
   "category": "suspected",
   "definition_type": "case_definition",
   "description": "Case definition for suspected cold exposure in individuals with history of extreme cold exposure during Early Temperature Extreme Alert by National Meteorological Service, and clinical symptoms attributable to low body temperature (36°C or lower) and 2 or more of the following: shivering, altered consciousness, weak pulse, slow breathing, local tissue damage due to freezing.",
   "human_readable_definition": "Toda persona con antecedentes de\nexposición a frío extremo en circunstancia de Alerta Temprana por Temperatura\nExtrema (frío) del Servicio Meteorológico Nacional, y sintomatología clínica\natribuible. Temperatura corporal igual o menor a 36 ºC y 2 o más de los siguientes\nsíntomas, a saber:\nSignos y síntomas atribuibles: escalofríos, alteración del estado de conciencia, pulso\ndébil, bradipnea, daño tisular local causado por el enfriamiento. Piel fría y roja en\nbebés.",
   "inclusion_criteria": [
     {
       "logical_operator": "AND",
       "type": "criterion",
       "values": [
         {
           "attribute": "body_temperature",
           "name": "Low body temperature",
           "operator": "\u003c=",
           "type": "symptom",
           "unit": "celsius",
           "value": 36
         },
         {
           "logical_operator": "AT_LEAST",
           "logical_operator_arguments": [
             2
           ],
           "type": "criterion",
           "values": [
             {
               "name": "Shivering",
               "type": "symptom"
             },
             {
               "name": "Altered consciousness",
               "type": "symptom"
             },
             {
               "name": "Weak pulse",
               "type": "symptom"
             },
             {
               "name": "Slow breathing",
               "type": "symptom"
             },
             {
               "name": "Local tissue damage due to freezing",
               "type": "symptom"
             },
             {
               "name": "Cold, red skin in babies",
               "type": "symptom"
             }
           ]
         }
       ]
     }
   ],
   "keywords": [
     "Cold",
     "South America",
     "Climate-related"
   ],
   "language": "English",
   "location": "Argentina",
   "notes": [
     "ICD-10 code COLD: X31 (Exposure to excessive natural cold)"
   ],
   "open_syndrome_version": "1.0.0",
   "organization": "Ministerio de Salud",
   "published_at": "2025-02-08T12:20:55Z",
   "published_by": [
     "Open Syndrome Initiative"
   ],
   "published_in": "https://opensyndrome.org",
   "references": [
     {
       "url": "https://www.argentina.gob.ar/sites/default/files/2019/10/msal-manual_de_normas_y_procedimientos_de_vigilancia_y_control_de_eno_2022.pdf"
     }
   ],
   "scope": "specific",
   "status": "draft",
   "target_public_health_threats": [
     "Cold"
   ],
   "title": "Open Syndrome Cold Exposure",
   "version": "1.0.0"
 }

Using the Definition #

Healthcare organizations can implement this definition through:

  • Direct integration with surveillance systems
  • API endpoints for real-time validation
  • Manual case verification processes

Next Steps #

We encourage:

  • Clinical feedback on the definition criteria
  • Technical feedback on the implementation format
  • Suggestions for additional symptoms or signs
  • Reports of implementation experiences

Get Involved #

We welcome contributions and feedback from the community.